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R Herbst Selected Research

dusigitumab

1/2017Overproduction of IGF-2 drives a subset of colorectal cancer cells, which specifically respond to an anti-IGF therapeutic antibody and combination therapies.

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R Herbst Research Topics

Disease

4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2018 - 08/2001
4Lymphoma (Lymphomas)
07/2012 - 08/2000
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 01/2002
3Melanoma (Melanoma, Malignant)
11/2020 - 01/2019
3Neoplasms (Cancer)
01/2017 - 01/2000
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
10/2017 - 03/2005
2Leukemia
07/2015 - 08/2000
2Myeloid Leukemia (Leukemia, Myelocytic)
02/2003 - 02/2000
1Basal Cell Carcinoma (Rodent Ulcer)
08/2021
1Uveal melanoma
11/2020
1Poliomyelitis (Polio)
11/2018
1Pathologic Complete Response
01/2018
1Colorectal Neoplasms (Colorectal Cancer)
01/2017
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2017
1Breast Neoplasms (Breast Cancer)
11/2016
1Carcinogenesis
11/2016
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
06/2013
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
06/2013
1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Leukemia, Pre B Cell)
06/2013
1Congenital Myasthenic Syndromes (Myasthenia Gravis, Congenital)
10/2005
1Hematologic Neoplasms (Hematological Malignancy)
02/2003
1Pneumonia (Pneumonitis)
01/2002
1Esophagitis
01/2002
1Hodgkin Disease (Hodgkin's Disease)
01/2001
1Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2001
1Residual Neoplasm
08/2000
1Glioma (Gliomas)
01/2000

Drug/Important Bio-Agent (IBA)

4Cytarabine (Cytosar-U)FDA LinkGeneric
01/2018 - 01/2001
3AntigensIBA
11/2018 - 08/2000
3Mitoxantrone (Novantrone)FDA LinkGeneric
01/2018 - 01/2001
2B7-H1 AntigenIBA
11/2020 - 01/2020
2Proteins (Proteins, Gene)FDA Link
11/2020 - 11/2016
2Phosphotransferases (Kinase)IBA
11/2016 - 02/2000
2Phosphoric Monoester Hydrolases (Phosphatases)IBA
02/2003 - 01/2000
2fludarabineIBA
08/2001 - 01/2001
1ErbB Receptors (EGF Receptor)IBA
01/2022
1HhAntag691IBA
08/2021
1Immune Checkpoint InhibitorsIBA
11/2020
1Biomarkers (Surrogate Marker)IBA
01/2020
1ImmunosorbentsIBA
01/2020
1EnzymesIBA
01/2020
1Programmed Cell Death 1 ReceptorIBA
01/2020
1VemurafenibIBA
01/2019
1VaccinesIBA
11/2018
1Daunorubicin (Cerubidine)FDA LinkGeneric
01/2018
1Amsacrine (AMSA)IBA
01/2018
1Insulin-Like Growth Factor II (Somatomedin A)IBA
01/2017
1Tyrosine Kinase InhibitorsIBA
01/2017
1Insulin-Like PeptidesIBA
01/2017
1dusigitumabIBA
01/2017
1LigandsIBA
01/2017
1human ERBB2 proteinIBA
11/2016
1Messenger RNA (mRNA)IBA
11/2016
1MucinsIBA
11/2016
1Humanized Monoclonal AntibodiesIBA
06/2013
1inebilizumabIBA
06/2013
1AntibodiesIBA
06/2013
1Methotrexate (Mexate)FDA LinkGeneric
04/2007
1Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric
04/2007
1Busulfan (Busulfex)FDA Link
04/2007
1muskIBA
10/2005
1Sirolimus (Rapamycin)FDA Link
03/2005
1Interleukin-6 (Interleukin 6)IBA
02/2003
1Tyrosine (L-Tyrosine)FDA Link
02/2003
1Morphine (MS Contin)FDA LinkGeneric
01/2002
1Amifostine (Ethyol)FDA LinkGeneric
01/2002
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
08/2001
1Cisplatin (Platino)FDA LinkGeneric
01/2001
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
08/2000
1integrin-linked kinaseIBA
01/2000
1Inositol (Myoinositol)IBA
01/2000
1LipidsIBA
01/2000
1Type C PhospholipasesIBA
01/2000

Therapy/Procedure

5Therapeutics
11/2020 - 01/2017
3Radiotherapy
01/2020 - 04/2007
3Drug Therapy (Chemotherapy)
01/2020 - 01/2001
3Stem Cell Transplantation
07/2012 - 12/2005
2Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
07/2012 - 04/2007
1Chemoradiotherapy
01/2020
1Hematopoietic Stem Cell Transplantation
02/2016
1Cell Transplantation
12/2005
1Salvage Therapy
08/2001